PROF. DR. MED. NIKOLAI HOPF, MD (USMLE)
"I DON'T SHAVE HAIR... HEALTHY PATIENTS SHOULD ALSO LOOK HEALTHY SOON AFTER SURGERY! "
Since the 1990s, Professor Hopf has played a decisive role in the development of endoscope-assisted microsurgery and endoscopic skull-base surgery, and has acquired special expertise in the transcranial and transnasal endoscopic treatment of tumours of the central cranial base (sella region), the brain stem and spinal cord, and the pineal region. From 2005 to 2014, Professor Hopf held a teaching position at the Johannes Gutenberg University (Mainz) and at the Eberhard Karls University in Tübingen.
From 2009 to 2012, Professor Hopf was editor-in-chief of the international journal “Minimally Invasive Neurosurgery” and subsequently of its successor “Innovative Neurosurgery”. Among other things, he has published extensively on the endoscopic treatment of hydrocephalus and arachnoid cysts and on the minimally invasive treatment of complex cerebral vascular diseases such as multiple brain aneurysms. His post-doctoral lecturing qualification paper discussed the migratory activity of brain tumour cells. Professor Hopf’s scientific interest continues to focus on neuro-oncology and the development of new minimally invasive surgical techniques and instruments.
Since the 1990s, Professor Hopf has played a decisive role in the development of endoscope-assisted microsurgery and endoscopic skull-base surgery, and has acquired special expertise in the transcranial and transnasal endoscopic treatment of tumours of the central cranial base (sella region), the brain stem and spinal cord, and the pineal region. From 2005 to 2014, Professor Hopf held a teaching position at the Johannes Gutenberg University (Mainz) and at the Eberhard Karls University in Tübingen.
PROFESSIONAL BACKGROUND
Medical Studies
Specialist education
Study mission
Senior Physician
Medical Director
Founding of NeuroChirurgicum
Foundation of ENDOMIN College
Relocation
Cooperations
Links
Endoscopic ventriculostomy
Endoscopic cyst fenestration
Endoscopic-assisted operation of skull-base epidermoid
Interview on Minimally invasive neurosurgery in "Lieder-Liebe-Leben"
Health seminar on the subject of "Living with cancer".
Selected publications:
Hopf NJ, Bremm J, Bohl J, Perneczky A (1994)
Image analysis of proliferating cells in tumors of the human nervous system: An immunohistological study using the monoclonal antibody Ki-67.
Neurosurgery 35: 917-923Hopf NJ, Füllbier L (2010)
Hopf NJ, Perneczky A (1998)
Endoscopic neurosurgery and endoscope-assisted microneurosurgery for the treatment of intracranial cysts.
Neurosurgery 43: 1330-1337
Hopf NJ, Grunert P, Fries G, Resch KDM, Perneczky A (1999)
Endoscopic third ventriculostomy: Outcome analysis of 100 consecutive procedures. Neurosurgery 44: 795-806
Hopf NJ, Grunert P, Darabi K, Busert C, Perneczky A (1999)
Frameless neuronavigation applied to endoscopic neurosurgery.
Minim Invas Neurosurg 42: 187-193
Hopf NJ (1999)
Endoscopic neurosurgery „around the corner“ with a rigid endoscope.
Minim Invas Neurosurg 42: 27-31
Kanner A, Hopf NJ, Grunert P (2000)
The „optimal“ burr hole position for endoscopic third ventriculostomy: results from 31 stereotactically guided procedures.
Minim Invas Neurosurg 43: 187-189
Demuth T, Hopf NJ, Kempski O, Sauner D, Herr M, Giese A, Perneczky A (2001)
Migration activity of human glioma cell lines in vitro assessed by continuous single cell observation.
Clin Exp Metastas 18: 589-597
Koch D, Grunert P, Filippi R, Hopf NJ (2002)
Re-ventriculostomy for treatment of obstructive hydrocephalus in cases of stoma dysfunction.
Minim Invasiv Neurosurg 45: 158-163
Hopf NJ, Stadie A, Reisch R (2009)
Management of bilateral middle cerebral artery aneurysms via a Unilateral Supraorbital
Key-Hole Craniotomy
Minim Invasiv Neurosurg 52: 126-131
Reisch R, Stadie A, Kockro R, Gawish I, Schwandt E, Hopf NJ (2009)
Supraorbital subfrontal key-hole approach for surgical treatment of temporomesial lesions of the dominant hemisphere
Minim Invasiv Neurosurg 52: 163-169
Hopf NJ, Füllbier L (2010)
Minimally invasive neurosurgery for vascular lesions.
Neurosurg Clin N Am 21(4): 673-689
Fischer G, Stadie A, Reisch R, Hopf NJ, Fries G, Böcher-Schwarz H, van Lindert E, Ungersböck K, Knosp E, Oertel J, Perneczky A (2011)
The keyhole concept in aneurysm surgery: results of the past 20 years.
Neurosurgery 68 (1 Suppl Operative):45-51; discussion 51.
Coburger J, Musahl C, Henkes H, Horvath-Rizea D, Bittl M, Weissbach C, Hopf N (2012)
Comparison of navigated transcranial magnetic stimulation and functional magnetic resonance imaging for preoperative mapping in rolandic tumor surgery
Neurosurg Rev 36: 65-75, discussion 75-76
Coburger J, Karhu J, Bittl M, Hopf NJ (2012)
First preoperative functional mapping via navigated transcranial magnetic stimulation in a 3-year-old boy.
J Neurosurg Pediatr 9 (6): 660-664
Reisch R, Stadie A, Kockro RA, Hopf N (2012)
The keyhole concept in Neurosurgery.
World Neurosurg 79 (2 Suppl); p. S17.e9-13 /201302/
Kurucz P, Baksa G, Patonay L, Hopf NJ (2013)
Endoscopic anatomical study of the arachnoid architecture on the base of the skull: Part I: The anterior and middle cranial fossa
Innovative Neurosurgery 1(1): 55-66
Kurucz P, Baksa G, Patonay L, Hopf NJ (2013)
Endoscopic anatomical study of the arachnoid architecture on the base of the skull: Part II: Level of the tentorium, posterior cranial fossa and the craniovertebral junction
Innovative Neurosurgery 1(2): 91-108
Hopf NJ, Kurucz P, Reisch R (2013)
Three-dimensional HD endoscopy – first experiences with the Einstein Vision system in neurosurgery
Innovative Neurosurgery 1(2): 125-131
Renovanz M, Gutenberg A, Haug M, Strittmacher E, Mazur J, Nadji-Ohl M, Giese A, Hopf N (2013)
Postsurgical screening for psychological disorders in neurooncological patients
Acta neurochirurgica; VOL: 155 (12); p. 2255-61 /201312/
Renovanz M, Hickmann A-K, Henkel C, Nadji-Ohl M, Hopf NJ (2014)
Navigated versus non-navigated intraoperative ultrasound: is there any impact on the extend of resection of high-grade gliomas? A retrospective clinical analysis.
J Neurol surg A 75: 224-230
Thaher F, Kurucz P, Fuellbier L, Bittl M, Hopf NJ (2014)
Endoscopic surgery for tumors of the pineal region via a paramedian infratentorial supracerebellar keyhole approach (PISKA)
Neurosurgical Review 37: 677-684
Hickmann A; Nadji-Ohl M; Hopf NJ (2014)
Feasibility of fluorescence-guided resection of recurrent gliomas using five-aminolevulinic acid: retrospective analysis of surgical and neurological outcome in 58 patients.
Journal of neuro-oncology /20150104/
Reisch R; Fischer G; Stadie A; Kockro R; Cesnulis E; Hopf N (2014)
The Supraorbital Endoscopic Approach for Aneurysms.
World neurosurgery; VOL: 82 (6S); p. S130-S137
Renovanz M; Hickmann AK; Gutenberg A; Bittl M; Hopf NJ (2015)
Does size matter? Minimally invasive approach in pediatric neurosurgery–a review of 125 minimally invasive surgeries in children: clinical history and operative results. Childs Nerv Syst. 2015;31(5):665-74
Thaher F, Hopf N, Hickmann AK, Kurucz P, Henkes H, Feigl G (2015)
Supraorbital keyhole approach to the skull base: evaluation of complications related to CSF fistulas and opened frontal sinus.
J Neurol Surg A Cent EUR Neurosurg; 76(6): 433-7
Hickmann A-K; Nadji-Ohl M; Haug M; Hopf NJ; Ganslandt O; Giese A; Renovanz M (2016)
Suicidal ideation, depression, and health-related quality of life in patients with benign and malignant brain tumors: a prospective observational study in 83 patients
Acta Neurochir; DOI 10.1007/s00701-016-2844-y
Lan Q, Sughrue M, Hopf NJ, Mori K, Park J, Andrade-Barazarte H, Balamurugan M, Cenzato M, Broggi G, Kang D, Kikuta K, Zhao H, Irie S, Li Y, Liew BS, Kato Y (2019)
International expert consensus statement about methods and indications for keyhole microneurosurgery from International Society on Minimally Invasive Neurosurgery.
Neurosurg Rev; 21, DOI 10.1007/s10143-019-01188-z
Bücher (Herausgeber)
Hopf NJ, Tonn J (Hrsg)
Neurochirurgische Akademie: Vaskuläre Neurochirurgie, Funktionelle Neurochirurgie
Georg Thieme Verlag Stuttgart-New York, 2011
Reisch R, Hopf N (Hrsg)
Transcranial Endoscope-Assisted Microsurgery: A practical Atlas
Aesculap AG
Ausgewählte Buchbeiträge
Hopf NJ, Resch KDM, Ringel K, Perneczky A:
Endoscopic Management of Intracranial Arachnoid Cysts.
In: Hellwig D, Bauer LB (edts): Minimally Invasive Techniques for Neurosurgery, Springer Verlag Berlin Heidelberg New York, pp: 111-119, 1998
Hopf NJ, Füllbier L:
Minimally invasive Neurosurgery for vascular lesions
In: Sughrue, Teo (Edts.): Neurosurgery Clinics of North America: Minimally Invasive Intracranial Surgery, Elsevier Verlag New York, 2010
Hopf NJ:
Nichtrupturierte Aneurysmen: Zeitbombe im Kopf
In: Hopf, Tonn (Hrsg): Neurochirurgische Akademie: Vaskuläre Neurochirurgie, funktionelle Neurochirurgie, Thieme Verlag Stuttgart New York, 2011
Steiger H-J, Hopf NJ:
Arteriovenöse Malformationen: Klassifikation
in: Hopf, Tonn (Hrsg): Neurochirurgische Akademie: Vaskuläre Neurochirurgie, funktionelle Neurochirurgie, Thieme Verlag Stuttgart New York, 2011
Musahl C, Schul C, Hopf NJ:
Intraoperative Indozyaningrün (ICG)-Fluoreszenzangiographie „IR 800“ der Firma ZEISS
in: Hopf, Tonn (Hrsg): Neurochirurgische Akademie: Vaskuläre Neurochirurgie, funktionelle Neurochirurgie, Thieme Verlag Stuttgart New York, 2011
Hopf NJ, Musahl C, Henkes H:
Carotid Cavernous Fistulas: Part I: Presentation and Features
in: Spetzler, Kalani, Nakaji (Hrsg): Neurovascular Surgery, 2nd Edition,
Thieme Verlag Stuttgart – New York, 2015
Musahl C, Weissbach C, Hopf NJ:
Neuromonitoring
in: Spetzler, Kalani, Nakaji (Hrsg): Neurovascular Surgery, 2nd Edition,
Thieme Verlag Stuttgart – New York, 2015
Musahl C and Hopf NJ:
Neuromonitoring for arteriovenous malformation surgery
in: Spetzler RF, Kondziolka DS, Higashida RT, Kalani MYS: Comprehensive Management of Arteriovenous Malformations of the Brain and Spine
Cambridge University Press, 2015
Hopf NJ, Reisch R, P Kurucz:
Neurovascular Compression Syndromes
in: König A, Spetzger U: Skull Base Surgery – Schädelbasischirurgie
Springer International Publishing, 2018
DOI: 10.1007/978-3-319-64018-1
Hopf NJ and Gardner PA:
Intracranial Aneurysms
in: Evans JJ, Kenning TJ, Farrell C, Kshettry V (Hrsg): Endoscopic and Keyhole Cranial Base Surgery
Springer International Publishing, 2019
DOI: 10.1007/978-3-319-64379-3
Hopf N, Reisch R:
Skull Base Approaches: Supraorbital
in: Raabe A (Hrsg): The Craniotomy Atlas
Thieme Verlag Stuttgart, 2019
Hopf NJ.
Tumors of the anterolateral skull base: anterior clinoid: Perspective
in: Jean W (Hrsg): Skull base surgery: strategies
Thieme Verlag New York-Stuttgart-Delhi-Rio de Janeiro, 2019DOI: 10.1017/S0022215119001221
Musahl C, Hopf NJ:
Neuromonitoring for brainstem surgery
in: Spetzler, Kalani, Lawton (Hrsg): Surgery of the brainstem
Thieme Verlag New York-Stuttgart-Delhi-Rio de Janeiro, 2020
DOI: 10.1055/b-006-164726